Investigation of ultrasound and low-frequency vibration for glycometabolism promotion in 3T3-L1 adipocytes

Dr. Daijiro Haba, RPT, Ph.D. Postdoctoral Fellow in Global Nursing Research Center

Low-frequency vibration (LFV) was found to be effective against DFUs and promoted blood flow in diabetic wounds by improving glycometabolism. Previous studies have revealed that ultrasound (US) therapy also promotes wound healing in DFUs; however, it is unclear whether it improves glycometabolism during wound healing. This study investigated the efficiency of LFV and US therapy in promoting glucose uptake in 3T3-L1 adipocytes. This study revealed that exposure of adipocytes to LFV improved glycometabolism, whereas high-intensity US irradiation reduced the number of lipid droplets.

Access the full paper here: https://doi.org/10.57337/jjeapt.2023-001